Chromosome Instability and Dynamics
Dr. Avi Matityahu
Areas of Interest
Research
Chromosome Instability and Dynamics
Teaching
2009- Today Lecturer in courses:
1.General and inorganic chemistry.
2.Clinical molecular biology.
Publications
21. Elias, M., Gani, S., Lerner, Y., Yamin, K., Tor, C., Patel, A., Matityahu,
A., Dessau, M., Qvit, N., Onn, I., Developing a peptide to disrupt cohesin head domain interactions,
ISCIENCE (2023), doi: https://doi.org/10.1016/j.isci.2023.107498.
Current impact factor: 6.107
20. Matityahu A and Onn I (2022) It’s all in the numbers: Cohesin stoichiometry. Front. Mol. Biosci. 9:1010894. doi: 10.3389/fmolb.2022.1010894
Current impact factor: 6.113
19. KatreenaYamin, Swati Bijlani, Judith Berman, Awakash Soni, Joseph Shlomai, Bijoy Mukut Buragohain, Michal Werbner, MeitalGal‑Tanamy, Avi Matityahu, Itay Onn1. Fold-change of chromatin condensation in yeast is a conserved property. Sci Rep 12, 17393 (2022). https://doi.org/10.1038/s41598-022-22340-8.
Current impact factor: 4.996
18. Matityahu A, Onn I. Hit the brakes - a new perspective on the loop extrusion mechanism of cohesin and other SMC complexes. J Cell Sci. 2021 Jan 8;134(1):jcs247577. doi: 10.1242/jcs.247577. PMID: 33419949.
Current impact factor: 4.573
17. Pathania A, Liu W, Matityahu A, Irudayaraj J, Onn I. Chromosome loading of cohesin depends on conserved residues in Scc3. Curr Genet. 2021 Jan 6. doi: 10.1007/s00294-020-01150-3. Epub ahead of print. PMID: 33404730.
Current impact factor: 3.661
16. Wenjie Liu, Elisheva Biton, Anjali Pathania, Avi Matityahu, Joseph Irudayaraj and Itay Onn. Monomeric cohesin state revealed by live‐cell single‐molecule spectroscopy. EMBO Rep (2020)21:e48211 https://doi.org/10.15252/embr.201948211.
Current impact factor: 8.383
15. Yamin, K., Assa, M., Matityahu, A. and Itay Onn. Analyzing chromosome condensation in yeast by second-harmonic generation microscopy. Curr Genet (2019). https://doi.org/10.1007/s00294-019-01034-1
Current impact factor: 3.464
14. Boginya, A., Detroja, R., Matityahu, A. et al. The chromatin remodeler Chd1 regulates cohesin in budding yeast and humans. Sci Rep 9, 8929 (2019). https://doi.org/10.1038/s41598-019-45263-3
Current impact factor: 4.525
13. Matityahu A., Shwartz M., Onn I. (2019) Identifying Functional Domains in Subunits of Structural Maintenance of Chromosomes (SMC) Complexes by Transposon Mutagenesis Screen in Yeast. In: Badrinarayanan A. (eds) SMC Complexes. Methods in Molecular Biology, vol 2004. Humana, New York, NY
12. Shira Perez, Michael Gevor, Ateret Davidovich, Antony Kaspi, Katreena Yamin, Tom Domovich, Tomer Meirson, Avi Matityahu, Yehuda Brody, Salomon M Stemmer, Assam El- Osta, Izhak Haviv, Itay Onn and Meital Gal-Tanamy. Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host- virus interactions. Nucleic Acids Res. 2019. https://doi.org/10.1093/nar/gkz052.
Current impact factor: 11.561
11. Matityahu, A. & Onn, I. Curr Genet (2017). A new twist in the coil: functions of the coiled-coil domain of structural maintenance of chromosome (SMC) proteins. https://doi.org/10.1007/s00294-017-0735-2.
Current impact factor: 3.764
10. Ola Orgil, Hadar Gershon, Avi Matityahu and Itay Onn. (2016) Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity. Nucleic Acids Res. 2016 : gkw539v1-gkw539.
Current impact factor: 9.202
9. Shwartz M., Matityahu A., Onn I. (2016) Identification of functional domains in the cohesin loader subunit Scc4 by a random insertion/dominant negative screen. G3 (Bethesda). 2016 Jun 8. pii: g3.116.031674. doi: 10.1534/g3.116.031674
Current impact factor: 3.20
8. Orgil O, Matityahu A, Eng T, Guacci V, Koshland D, Onn I (2015) A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex. PLoS Genet 11(3): e1005036. doi:10.1371/journal. pgen.1005036.
Current impact factor: 7.53
7. Matityahu, A., Sitruk, A., Hadar, Y. and Belinky, P.A. (2015) Factors Affecting the Induction of Lignin Peroxidase in Manganese-Deficient Cultures of the White Rot Fungus Phanerochaete chrysosporium. Advances in Microbiology, 5, 83-92. http://dx.doi.org/10.4236/aim.2015.52009
Current impact factor: 0.56
6. Matityahu, A., Hadar, Y., and Belinky, P.A. (2010). Involvement of protein kinase C in lignin peroxidase expression in oxygenated cultures of the white rot fungus Phanerochaete chrysosporium. Enzyme Microb. Technol. 47: 59-63.
Current impact factor: 2.32
5. Matityahu, A., Hadar, Y., Dosoretz, C.G., and Belinky, P.A. (2008). Gene Silencing by RNA Interference in the White Rot Fungus Phanerochaete chrysosporium. Appl. Environ. Microbiol. 74(17): 5359–5365.
Current impact factor: 3.823
4. Matityahu, A., Stern R.A., Schneider, D. and Goldway, M. (2005). Molecular identification of a new apple S-RNase – S-29 – cloned from Anna, a low chilling requirement cultivar. HortScience 40: 850-851.
Current impact factor: 0.943
3. Y. Chowers · A. Matityahu · N. Keller · S. Bar-Meir · M. Goldway. (2002). E-coli secreting short chain variable fragments protect from intestinal salmonellosis. Gastroenterology 122(4):A44-A44.
Current impact factor: 18.187
2. Goldway, M., Schneider, D.,Yehuda, H., Matityahu, A., Eisikowitch D. and Stern R.A. (2001). The effect of apple S-allele compatibility on fruit-set level in non-optimal fertilization conditions. Acta horticulture. 561:231-234.
Current impact factor: 0.17
1. Martin Goldway, Osnat Shai, Hila Yehuda, Avi Matityahu and Raphael A. Stern (1999). ‘Jonatan’ apple is a lower-potency pollenizer of ‘Topred’ than ‘Golden Delicious’ due to partial S-allele incompatibility. Journal of horticultural science and biotechnology 74(3): 381-385.
Current impact factor: 0.54